1. Welcome to Autism Forums, a friendly forum to discuss Aspergers Syndrome, Autism, High Functioning Autism and related conditions.

    Your voice is missing! You will need to register to get access to the following site features:
    • Reply to discussions and create your own threads.
    • Our modern chat room. No add-ons or extensions required, just login and start chatting!
    • Private Member only forums for more serious discussions that you may wish to not have guests or search engines access to.
    • Your very own blog. Write about anything you like on your own individual blog.

    We hope to see you as a part of our community soon! Please also check us out @ https://www.twitter.com/aspiescentral

Featured Autism traits could be 'edited' out genetic trial suggests

Discussion in 'Autism Spectrum News, Events and Research' started by AGXStarseed, Jun 28, 2018.

  1. AGXStarseed

    AGXStarseed Well-Known Member

    Messages:
    4,462
    Joined:
    Jun 13, 2013
    Karma:
    +5,487
    (Not written by me)

    [​IMG]
    The study on mice used gold nanoparticles to target genes causing repetitive behaviour CREDIT: SOLOMON BANDA


    Autism traits may be “edited” out using new genetic techniques, scientists have said, following a successful trial.

    Researchers are hailing a breakthrough after they used cutting-edge gene editing to to significantly reduce repetitive behaviour associated with the disorder.

    The technique, which was performed on mice, could also be developed to treat conditions ranging from opioid addiction and neuropathic pain to schizophrenia and epileptic seizures.

    Scientists injected gold nanoparticles covered in a “forest” of DNA chains to alter the the genetic code of mouse models with a form of autism called fragile X syndrome (FXS).

    The technique, CRISPR-Cas9 gene editing, resulted in in a 30 per cent drop in repetitive digging, and a 70 reduction in leaping, both indicative of autistic behaviour.

    Because the editing DNA was introduced attached to gold particles, the team were able to control how much of the crucial Cas9 protein was delivered, in contrast to previous failed attempts using viruses.

    "There are no treatments or cures for autism yet, and many of the clinical trials of small-molecule treatments targeting proteins that cause autism have failed," said study leader Hye Young Lee, an assistant professor of cellular and integrative physiology at the University of Texas Health Science Center at San Antonio.

    "This is the first case where we were able to edit a causal gene for autism in the brain and show rescue of the behavioral symptoms."

    Autism spectrum disorder is a complex developmental disorder, with a strong genetic component, which manifests during childhood.

    It is characterised by deficits in the domain of social interaction and communication, stereotyped behaviour, delayed speech and language and can also be associated with intellectual disability.

    There are around 700,000 people on the autism spectrum in the UK - more than one in 100 - and when including families, it is a part of daily life for 2.8 million people.

    The results are published in the journal Nature Biomedical Engineering.


    Source: Autism traits could be 'edited' out genetic trial suggests
     
    • Informative Informative x 1
  2. Fridgemagnetman

    Fridgemagnetman I only have one V.I.P Member

    Messages:
    6,246
    Joined:
    Jan 31, 2017
    Karma:
    +12,724
    Maybe they should just turn us into mice.
     
    • Funny Funny x 6
    • Like Like x 2
    • Agree Agree x 1
  3. Progster

    Progster Gone sideways to the sun V.I.P Member

    Messages:
    5,863
    Joined:
    Nov 23, 2014
    Karma:
    +12,511
    Yes, they did a pretty good job of running the planet.
     
    • Funny Funny x 6
    • Like Like x 2
    • Agree Agree x 2
  4. Judge

    Judge Well-Known Member V.I.P Member

    Messages:
    23,879
    Joined:
    Aug 28, 2013
    Karma:
    +30,390
    Society at its worst- driven through genetic engineering. See the movie instead. <Facepalm>

    [​IMG]
     
    • Agree Agree x 4
    • Like Like x 1
    • Funny Funny x 1
  5. Suiseiseki

    Suiseiseki I can't feel the back of my eyes

    Messages:
    384
    Joined:
    Jan 24, 2010
    Karma:
    +192
    i wouldn't want my children to have autism or schitzophrenia.
     
    • Agree Agree x 1
  6. Nitro

    Nitro Admin/Immoral Turpitude Staff Member Admin V.I.P Member

    Messages:
    9,866
    Joined:
    Apr 5, 2014
    Karma:
    +17,582
    So where do you draw the line between a cure and eugenics?
     
    • Agree Agree x 8
    • Like Like x 1
  7. VJCJ0628

    VJCJ0628 Well-Known Member

    Messages:
    697
    Joined:
    Jun 8, 2018
    Karma:
    +313

    That's the thing nothing Bad is ever introduced as harmful, Its always introduced as helpful, Ie Euginetics even Hitlers solution, Besides the more extream examples you see every day, The TV commercials, if you took this med (the number one med 20 years ago) you are entitled to this settlement because it was found to cause all these crazy effects over the long-term, there are many more examples

    Listen how much the advertising the coming driverless cars are tested so safe 100%, Anything that says otherwise is misinfo, Yea then when they started hitting the road they had to pull them off because of accidents
     
    • Like Like x 1
  8. Bella Pines

    Bella Pines Well-Known Member V.I.P Member

    Messages:
    898
    Joined:
    Jun 6, 2017
    Karma:
    +1,883
    I honestly doubt they will get anywhere. It's part of who we are. It's like saying there is a cure for excessively jolly and optimistic people. Which I suppose wouldn't be terrible. I hate the perpetually jolly and optimistic type.

    However, I firmly believe that a cure for neurotypicals is much closer. A simple hormone suppressant would do the trick. I'm thinking aerial delivery...
     
    • Funny Funny x 6
    • Like Like x 5
    • Agree Agree x 5
  9. Suiseiseki

    Suiseiseki I can't feel the back of my eyes

    Messages:
    384
    Joined:
    Jan 24, 2010
    Karma:
    +192
    I simply don't want any future children to have to struggle like I did, like I do, maybe struggle worse.
    Reading about the American Civil War as much as I do doesn't make things happy, it's not a fun life, and I know most people with autsim aren't happy with it.
    And most of us aren't genius inventors or any such thing either.
     
    • Agree Agree x 3
  10. Shamar

    Shamar Well-Known Member V.I.P Member

    Messages:
    424
    Joined:
    Apr 11, 2018
    Karma:
    +1,118
    As i said in an earlier thread, nearly the same subject, curing disease with genetics scares me silly.
     
    • Agree Agree x 1
  11. GrownupGirl

    GrownupGirl Tempermental Artist

    Messages:
    1,141
    Joined:
    Apr 30, 2018
    Karma:
    +1,905
    Can they find a way to genetically induce traits in NTs like acceptance and tolerance?
     
    • Winner Winner x 7
    • Like Like x 5
    • Agree Agree x 4
  12. Shamar

    Shamar Well-Known Member V.I.P Member

    Messages:
    424
    Joined:
    Apr 11, 2018
    Karma:
    +1,118
    A lack of those traits is not considered a disability or disease. In fact, in many cases those are considered desirable characteristics. No "cure" needed, doing so is a waste of time and money.

    I would rather stay like this than become like them.
     
  13. onlything

    onlything Well-Known Member V.I.P Member

    Messages:
    1,145
    Joined:
    Sep 6, 2017
    Karma:
    +2,256
    Would you have a choice if it came to your child? Or would all 'undesirables' need to be changed/exterminated?

    As I said many times before, I wouldn't like to be anyone else but myself. Repetitions? Obsessions? It's a part of me, however troublesome or not.
     
    • Agree Agree x 4
  14. Catana

    Catana Well-Known Member V.I.P Member

    Messages:
    290
    Joined:
    Feb 25, 2018
    Karma:
    +771
    What would the unanticipated side effects be of tampering with that gene? Assuming, of course, that those activities in mice are even remotely similar to human behavior.
     
    • Agree Agree x 4
  15. unreality

    unreality Well-Known Member

    Messages:
    69
    Joined:
    Jun 23, 2017
    Karma:
    +85
    I wouldn't trade the positive traits of autism for anything. I'd rather die than be an NT.
     
    • Agree Agree x 4
    • Winner Winner x 1
    • Friendly Friendly x 1
  16. WildCat

    WildCat and his scatterbrain V.I.P Member

    Messages:
    1,323
    Joined:
    Nov 14, 2010
    Karma:
    +1,648
    Some things need to be edited out of existence. ASD isn't one of them.

    A future where mediocrity isn't good enough? Sign me up! :emojiconfused:
     
    • Friendly Friendly x 1
  17. Smiley

    Smiley Well-Known Member

    Messages:
    103
    Joined:
    May 14, 2018
    Karma:
    +170
    Genetic modification of humans is illegal, isn't it? If it's not, it needs to be.
     
    • Agree Agree x 3
  18. Observant

    Observant Active Member

    Messages:
    152
    Joined:
    May 15, 2018
    Karma:
    +171
    I can understand the idea that you want a better life for your future kids, which is the reason why I don't want kids (it isn't Autism-related, it's more sociopolitical and environmental).

    However, with the pharmaceutical companies drive for profits combined the overzealous prescription of drugs this will do more harm to our community than good. We are seen as a problem that needs a solution, and they are profiting off of fear and misinformation. Ultimately this is an attempt to make us fit into a non-existent society where NTs say "this is who you need to be" rather than acknowledging the reality that society is so much more diverse and embracing that fact.

    I hate the "wanna be normal? Take a pill!" mindset that our society has, while showing us commercials that depict a sanitized upper-class version of reality.
     
    Last edited: Jun 28, 2018
    • Agree Agree x 2
  19. kay

    kay Well-Known Member

    Messages:
    1,199
    Joined:
    Jan 28, 2017
    Karma:
    +2,234
    Yeah, good point. And why are they worrying about autism so much when we need to be eliminating hate, violence, fascism, racism, lots and lots of isms. Modify genes so people stop killing one another, enjoying violence and the pain and suffering of others. Modify genes to eliminate greed and corruption. Modify genes to keep people from just meanness in general, from inconsiderate behaviors, and the love of all things loud and crowded. Autism doesn't seem to be such a big problem compared to some other things.
     
    • Agree Agree x 5
    • Winner Winner x 1
  20. Iamnotarabot

    Iamnotarabot Well-Known Member

    Messages:
    748
    Joined:
    Feb 3, 2018
    Karma:
    +840
    Thinking autism should be eradicated is thinking that diversity of mind should be eradicated,it reminds me of a not so distant past.
     
    • Agree Agree x 3
    • Like Like x 2