Unfortunately, I can relate to your extreme sensitivities to medication. Some thoughts: First, I'm concerned that you're trying escitalopram after having worrisome problems with citalopram. I hope that you and your doctor realize that escitalopram is the "left-enantiomer" of citalopram. If whatever caused your problems with citalopram is still present in escitalopram, you could be in trouble. Second, have you tried starting at extremely low doses of psych meds and increasing them very gradually, to help you adjust better? Escitalopram comes in a liquid, and you could measure it with an oral syringe. For medications that don't come in liquids, you can usually get the doses you want by going to a compounding pharmacist. Third, have you tried vilazodone (Viibryd)? It's relatively new, and acts like a combination of an SSRI and buspirone (Buspar). If, as you indicate, you're sensitive to medications and you've already tried a number of SSRIs, your doctor might be assuming that vilazodone isn't worth trying, but it's been very promising so far for me, once I figured out that my psychiatrist had overestimated the target therapeutic dose. However, I've had to have it compounded and adjust it by 1 mg/day every few days. And of course, different drugs work for different people. Which leads to my last question: have you had pharmacogenomic testing? I can't personally vouch for its validity, but here in the United States, Medicare is convinced enough of its usefulness that it's paying for it. The testing that my doctor used, Genesight, actually listed vilazodone as one of the recommended drugs for me, after I had already been on it, and had concerns about drugs that I've had trouble with. The recommendations aren't perfect, but they might help. Good luck!