Hello, I just saw page 1 to 3 of this interesting thread, but would like to share some personal view on the topic before I go to sleep (and probably forget about it).
I am more on the big picture, INTJ pattern conection mode. It may give a complementary view to some of you, as your detailed view is complementing mine.
I live in Mexico City, which is the middle of an artificial division of an actual building to building conclomerate of about 25 millions of people that is imaginary divided into many cities. Most of people here use public transportation, just the metro moves about 5 million people a day. So I would say this is one of the best places in the world for a virus to spread. That said:
1- I totally agree that the virus targets genetically. In my family (about 200 people) on about 4 countries (Spain, Mexico, USA and Germany) no one has needed to go to the hospital or use oxigen, including my 6 aunts of 80+ years old. We do have obese people, people with hipertension and very crazy ones that go to parties ignoring the cuarentines... I do also know first hand, families where many people have gone with severe symthoms or die. So to me its clear that the distribution of the severe cases has a lot to do with genetics.
2- In Mexico is now official that the goverment hidden about 60% of the deaths. Some people did the match betwenn the official numbers and deaths certificates and the excess deaths to previous years. The goverment finally acknowledge having done this, and they keep doing it...

We also had many well reported cases of people who died because various reasons (like fails due to extreme fatige on medics) whose deaths certificates were labeled by "coronavirus". So let say that data is not that trustable (at least in Mexico).
3- I am amazed at what is happening now at Japan. They somehow managed to stop the spread of the previous Covid waves, they vacinated nearly all their people. Now they are being infected by a "less lethal" virus that should target "non vacinated" and are getting way more deaths way faster that before. This again makes sense with what Ronal said about vacines non being that efective on people who has the wrong genetics-health conditions combinations.
3.1- Is this is true, it leads me to think that countries who have been able to stop previous waves will be hit anyway despite vaccines. Even if all human beins were vaccinated, the virus is already jumping between other species... and some of the asintomatic ones may be becoming reservories of the virus...this is sad.

4- I am also amazed at how lineal deaths by time are in USA and other countries, I expected to see a very big change after vacinations but I am not so sure now. The same goes for world agregated data (I could not upload my screenshot, go to
COVID Live - Coronavirus Statistics - Worldometer search the "Total Deaths graphic", click on linear scale and see yourselves).
4.1- Its also interesting to note that the peaks between global waves are very equally spaced, I have no idea of why is that, but I have put a mental label on it because it is too simetric.
5- I have a coworker who had the 3 vacines, got infected 3 times over this years with almost no symtoms and this last infection (one month ago) hit him like a truck. He didnt die but almost needed oxigen and his lungs have got some damage, he is needing medicine to breath properly one month after being possitive and keeps coughing most of the day. So I think the risks are there even when we take care.
I think I had more to share, but I am already sleeping...zzzz
Hope this wall of text with lack of detailed data wont upset you. I will (or not) keep reading on this thread, a lot of your info and insigth was very interesting to me.
Hugs.
