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One of these days, Alice.

How about a self-sustaining, totally sealed, “bio-dome” here on earth. There hasn’t been one successful example of that, yet.
Yeah, Life is full of surprises. One big discovery for planetary pioneers at Biosphere was that concrete continues to absorb oxygen for many months after being poured. They had to break the seals to save the humans.
 
Yeah, Life is full of surprises. One big discovery for planetary pioneers at Biosphere was that concrete continues to absorb oxygen for many months after being poured. They had to break the seals to save the humans.
In the words of Doctor Ian Malcom, "Life finds a way."
 
The moon is extremely weird. Those that have thoroughly studied it...you know what I mean.

The primary issue will be having a water supply because it's seemingly not going to come from the moon itself. Secondary will be simply why the moon has so many craters. It's constantly hit by meteors that do not burn up / shrink up in an atmosphere like the Earth has. Whatever is built there will have to withstand ongoing damage. "Build it underground, then?" I don't think so. Again, back to if one has truly, thoroughly studied the moon. There's a lot going on with that sphere that needs answered and way more thoroughly explored.
 
I think that for the foreseeable future, the only way to establish a self-supporting enterprise off the Earth is to mine Asteroids using robots.
 

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