From experience, plus reading Tony Attwood's Complete guide to Asperger's, I would say YES. Having ASD genetics plus a cluster B type attitude and behaviour is possible and I know the type only too well.
I prefer to refer to such individuals as "Cluster B" now, as a lot of the symptoms overlap, in my experience and it's difficult to diagnose such pathologically dishonest, grandiose and narcassistic individuals as they are VERY good at lying. They, typically, would NEVER allow themselves to be diagosed, yet their victims will flock, in droves, to psychiatrists and psycholgists.
My ex, I believe, is one such individual, and very likely, my mother's mother.
It is more likely in Autistic people who do not develop any kind of healthy sense of self, to the point where they wouldn't acknowledge their autism because they would feel "diminished" and they are intelligent enough to mask and not just as, typically, HFA females do, but with elaborate dishonesty and often criminal or manipulative "entitled" behaviour. Severe neglect and trauma in childhood often accompany this comorbid personality disordered pathology.
The key distinctions for "Cluster B" personality disordered people are a sense of entitlement and a proclivity to exploit others, often accompanied by drug or alcohol or food addictions, other's may have sex or money addictions.
They actually despise themselves (IMO) but due to their refusal to develop self awareness or accountability, they project their hatred and sense of inferiority onto other's.
My ex is obsessed with weed, like TOTALLY obsessed. He is utterly irresponsible and lies continually. He has boasted about how he has destroyed people's lives. He has no ability to emotionally support others or act with any empathy. He is VERY inflexible. He manipulates in typical ways - playing the victim when he has actually been the abuser, strawman arguments, stick and carrot ploys, emotional bullying, defaming others and exaggerating his own achievements, claiming credit for other's acheivements, and it really appears that he believing his own lies, he is so good at lying. Tony Attwood talks about dishonest Aspies, in the book and his description fits my ex
I told my children I believe he has ASD because it's a kinder assessment than the other and it does fit, but he seems to think he is a better person then everyone else so there is NO WAY he will reduce himself by getting diagnosed. He has been in jail and still practises a criminal life, so, contrary to common thought, psychopathic types can be scared of something, they do not want to get caught and made to stop their illegal activities, and they don't want to lose credibility, because it's harder to predate on others when "the gig is up" and people know what sort of people they are, THEY don't even want to know how ill they are, they want to keep feeling entitled, superior and getting away with their crimes and exploitations. So, commonly, the last thing these types of people will do, is get diagnosed.
I spent 20 years with my ex, from the age of 16 (he was twice my age) to 37, so, I figure, with my IQ (145) my special interest in clinical acience, autism and deviant personality disorders, I'm pretty entitled to speculate on my ex's particular pathology.
My youngest son, believes he, himself, has a "psychopath's brain" but due to my honesty-insisting, attentive, boundaried, and kind parenting (plus lots of help from my boyfriend) he has chosen to curb those impulses to hurt and manipulate others, he also has autistic and "gifted" traits. He literally has said, many, many times "I would be a psychopath, if it wasn't for you, mum".
Like his father, he has a propensity to be
manipulative and enjoy other's pain and sense of control over other's, but, unlike his father, he is honest, self aware and knows right from wrong, so he is constantly pulling himself up from treating other's badly.
I, however, am way too guileless, honest and autistic to be manipulative, and I'm extremely empathetic and morally drlven. My kid trust's me and admires me, so I think he will turn out ok.