Maybe this new drug will cure autism?

[Kayla55]

https://scitechdaily.com/a-drug-that-cures-autism-neuroscience-study-yields-promising-results/

 

[Ronald Zeeman]

I would not take something that changes who I am. Would not give this gift away for anything.

 

[Kayla55]

Side effects
These
include dizziness, headache, and nausea. Other Lamictal side effects are rare but more serious. These include rash, low blood cell levels, and an increase in suicidal thoughts and behaviors. Lamictal has a boxed warning for serious, life-threatening rash.26 Oct 2022

Similar to epilum....it may affect autism in a bad way, dont like blood ell levels, also create osteoporosis.

I think seratonin and Australian research needs more research. Epilepsy may have simar bone deficiencies and digestive issues with blood pressure.
This is a meds I don't like thinking of giving to a child. Reminds me of questioning Kimo....is it worth damage....surely we could do better in medical science, now I wish I'd studied this.

 

[Neonatal RRT]

This is an animal model. This implies that there is a such thing as a genetically-altered "autistic" mouse. Does this imply that we "know" what causes autism? How does one identify an "autistic" mouse? Mice are not humans. It is quite common for studies in mice not to translate to primates and humans. Mice with "autistic-like behavior" does not mean autistic mice.

Of the 100+ familial genes, the 1000+ de novo/epigenetic genes, and some 4000+ RNA transcription genes associated with autism, they chose to target one, and then make some claim that this single gene can be altered with a medication, and "reverse" autism. Sounds like a load of horse crap.

Furthermore, is this sodium-channel blocker specific to the brain, or is it relatively non-specific? If it is the later, then consider that sodium channels are found in nearly all of our tissues. Do we not expect some horrible side effects?

 

[Luca]

I take Lamotrigine for medical reasons, and I am absolutely not cured of autism.
I agree with Ronald Zeeman on this one.

 

[Kayla55]

I was chatting online and we discussed eating raw liver as old fashioned insulin and got me thinking of penacillin again. It is a mold grown on wheat n barley....also medicine from funny foods.
Now anti-biotics is hailed as miracle drug. scare into resistant strands....
Lookup factory farming and antibiotic resistance. Aside from I hate the cruelty on those farms, I'm wondering what health affects there are, also drinking long life or germ free milk.

Old people also produce less insulin, and have array of health issues. (A similar effect 'can' be diabetes 1 or epilepsy and I'm just exploring possibilities here of digestive issues exacerbate health)
Gut microbial changes in elderly individuals correlate with measures of frailty, nutritional status, and markers of inflammation, suggesting that diet-driven microbiota alterations play a role in the varying rates of age-associated health decline

metabolic, defensive, and trophic functions (Guarner and Malagelada, 2003)

However, they discovered that germ-free animals required large quantities of nutrient-rich food, yet continued to have stunted growth and development compared with normal animals. Germ-free animals had smaller hearts, lungs, and livers, lower cardiac output, thinner intestinal walls, reduced gastrointestinal motility, lower serum gamma globulin levels, and atrophied lymph nodes (Wostmann, 1981). Most of these deficiencies can be restored by introducing intestinal microbiota from animals raised under normal conditions.

 

[Kayla55]

Not to cure autism

I got crucified over type 1 & 2 diabetes for making suggestions that diet improves health, here I am simply exploring options for type 1 or epilepsy that could effect creation of insulin that's not diet specific.

Exercise and healthy eating are crucial to health, and with autism we may need few extra vitamins. This isn't to cure autism but basis on health issues related and using seratonin as model create less harmful drugs.

 

[BrokenBoy]

Seeing the title got me excited, but reading the thread made me disappointed.

 

[Ronald Zeeman]

I take Lamotrigine for medical reasons, and I am absolutely not cured of autism.
I agree with Ronald Zeeman on this one.

I don't think Alberta Einstein, would have been comfortable taking some drug to fix his autism, being such a burden.

 

[Kayla55]

This is an animal model. This implies that there is a such thing as a genetically-altered "autistic" mouse. Does this imply that we "know" what causes autism? How does one identify an "autistic" mouse? Mice are not humans. It is quite common for studies in mice not to translate to primates and humans. Mice with "autistic-like behavior" does not mean autistic mice.

Of the 100+ familial genes, the 1000+ de novo/epigenetic genes, and some 4000+ RNA transcription genes associated with autism, they chose to target one, and then make some claim that this single gene can be altered with a medication, and "reverse" autism. Sounds like a load of horse crap.

Furthermore, is this sodium-channel blocker specific to the brain, or is it relatively non-specific? If it is the later, then consider that sodium channels are found in nearly all of our tissues. Do we not expect some horrible side effects?

Autistic mouse may be explained in my late introduce yourself to the forum. A beautiful mind corrupted

 

[Xickin]

I would not take something that changes who I am. Would not give this gift away for anything.

Can I ask, why and how do you consider it a gift? I've only ever looked at it as an impediment and something to be ashamed of (until recently)

PS People aren't born with autism, they are born autistic, and realizing that made a huge difference in how I see this gift.

 

[Kayla55]

Society n people make life so difficult, being different makes it harder.
Yip, sometimes I feel the system gets me down, but I find inspiration, something grabs my attention. Not sure if I mask and behave so much like them, anymore.

Tired we battle on in life, harvested by prying eyes of capitalists who weave a synthetic model and commercialise and market to the masses. Our stolen identities, our silent tears...this world was never created with individual in mind.

 

[Butterfly88]

I already take Lamotrigine for my autism. It helps me manage my meltdowns somewhat better. In no way is it a cure. I don’t need to be cured of who I was meant to be.

 

[Slime_Punk]

I found something once that got rid of my symptoms, unfortunately it also made me act like a moron.

If there were a legit drug that would solve the issue without any side effects, however, I'd take it. I definitely consider my version of autism to be a problem in my life, but I totally get why others would feel the opposite for themselves.

 

[Alexej]

This is an animal model. This implies that there is a such thing as a genetically-altered "autistic" mouse. Does this imply that we "know" what causes autism? How does one identify an "autistic" mouse? Mice are not humans. It is quite common for studies in mice not to translate to primates and humans. Mice with "autistic-like behavior" does not mean autistic mice.

Of the 100+ familial genes, the 1000+ de novo/epigenetic genes, and some 4000+ RNA transcription genes associated with autism, they chose to target one, and then make some claim that this single gene can be altered with a medication, and "reverse" autism. Sounds like a load of horse crap.

Furthermore, is this sodium-channel blocker specific to the brain, or is it relatively non-specific? If it is the later, then consider that sodium channels are found in nearly all of our tissues. Do we not expect some horrible side effects?

Thank you for your post.
When I saw the title I thought I would not read more until you had jumped in and given a medical view on this.

Helpful as ever - thank you for being here

 

[Kayla55]

I already take Lamotrigine for my autism. It helps me manage my meltdowns somewhat better. In no way is it a cure. I don’t need to be cured of who I was meant to be.

Is it true more women suffer depression even resulting in suicide.
Young women described masking to point being so confused of who they are.
Mostly my experience of meltdowns was injustice or not understanding why I let others talk me into it.
I can't remember exactly when masking stopped, I think it was on my dear unhappiness and decision to do from now on what makes me happy, boy has my life being uphill struggle, it's shauvenism.

 

[Kayla55]

I never imagined myself as kind of girl that would throw a drink in a man's face, I'm quiet, I will shy away, try to get out back door, go home!!

But he was so provocative, insisting not just a dance but that I must show dance for him, so I gazed up (it was a dance venue and half a restaurant) I gazed up n suddenly realised the pole N saw drunk girls climbing on one another like rats to showcase....
Yip, he got drink in his face and this time adrenaline took me unhappy out front door.

Society has changed, men out there will respect you as much as you respect yourself. I remember being single many years and how I battled paying the bills ND protecting my right to choose to need freedom.

 

[Kayla55]

I'm venting here, but ask butterfly no. 88 about your satisfaction in masking.

So this example is purely surrounded by women at flea market stall and customers and me going out to sell my jewellery. I can do this, of course I can sell, it was my weakness but nonetheless. I'd started this hand making jewellery as hobby whilst kids busy. So surf contest came and I decided to get a stall at flea market. A friend found me someone to share the cost and amazing. Now I battled in small town to find right size gemstones, so after selling a few necklaces I went to chat to lady selling gemstones and looked and we talked about her angels. Wow, it was out of necessity that I needed these.
By end of flea-market my partner is showing signs of being a shop-a-holic and it's ok, she was a weird goth child, much younger ND reminded me of old friend college, Tammy.

I just didn't feel satisfied with girlie brigade of all stall and chit chat went so bland, I even felt I'd replicated to many pieces that were selling, weren't really unique just maybe hand made. (Sales) I prefer it as hobby, realised I wanted to do something with life again and that I was feeling annoyed by girlie show.

I think I took my mask and threw if against wall when I got home!

 

[Kayla55]

If I asked you to draw a list of potential hazards that cause meltdowns....

and then said can we avoid situation yes/no

Can you prepare a way of dealing with situation that would produce a better outcome.

I had being meltdown free for a long time, until people came in my life which drew situation into reverse.
So I had to seek to empower myself by finding a freelance position enabled me flexibility to work at my own pace.

The mind is powerful, so is ones will. When you combine these two then it is better than any drug.

I have a split personality in a management sense. One is the mask to deal with it and the other is my true self. In order to do this I have adapted an understanding of their world and mine. So it's twice as much work with a decided outcome. I've learnt not to always react, to have a reserved approach to even give the others space to be one walking off discontented at the manipulus of selfish I have reflected back to them
Not always perfect.

 

[Neonatal RRT]

If I asked you to draw a list of potential hazards that cause meltdowns....

and then said can we avoid situation yes/no

Can you prepare a way of dealing with situation that would produce a better outcome.

Personally, the number one trigger for meltdowns and shutdowns, is "autistic burnout". Basically, it is some combination of physical and mental exhaustion, poor sleep, too long of work hours, too much social interaction, poor nutrition, too much stress and anxiety, etc. Most people can deal with these sorts of things in the short term, a day or two, but if it is much longer, your ability to mask/camouflage, and to think rationally and clearly quickly fades. At this point is where I can turn into either a grumpy old man and/or become rather "scatter brained" and can no longer cope with daily stresses. All it would take is one seemingly innocuous "trigger" and I am either shutting down or lashing out violently.

For me, these things do not just suddenly happen, there's always some build-up to it. When I was young, stupid, and unaware of myself, I think I would "push myself" into these situations unknowingly. Now, I tend to pace myself, take "mini breaks" to collect myself, avoid known stressors as best I can, etc. It's about awareness and management.