Sugar is so inherently toxic while so many take it for granted. Though I'd think such toxicity would or could be accelerated with persons who have a minimal food intake in general. To me sugar is just another drug that can easily "play with your head".
When reducing my sugar isn't so much a struggle as it is a "war".
Sugar...glucose in the body...in and of itself is not "toxic", per se. Glucose, after all, is the primary intracellular source of energy. The larger problem, especially in excess, over time, can cause insulin insensitivity, metabolic syndrome, pre-diabetes, diabetes, obesity...and all the other downstream secondary health effects. The problem is the amount. In the US, sugar is added by manufacturers into all manner of processed foods, even in restaurant proprietary recipes...and humans are generally "hardwired" for "sweet things". After the first bite of your favorite sweet, your brain sends a signal that it wants "more"...triggering, in some, an addictive response and desire. As a business model, it makes sense...$$$.
If we look at this from the perspective of autism...excess dietary carbohydrates (complex sugars) presents as a mixed issue.
1. A rush of glucose into the brain can trigger the release of dopamine...initially making you feel better. Autism, being a low-dopamine condition...can be particularly sensitive.
2. Insulin, a hormone that is primarily responsible for carrying glucose into the cells, is released. However, insulin also has vasodilatory effects in the body and can shunt potassium into the cells, as well...both situations may be good or bad depending upon the situation.
3. The neurodevelopmental events associated with autism can leave the brain with a hyper metabolic condition, primarily a combination of minimal neuronal pruning in early childhood and in adolescence. Furthermore, we know that the neurons, themselves, are characterized by a significant increase in synaptic connections. On one hand, there is a relatively high demand for glucose, on the other hand, insulin-related vasodilation may cause an increase in intracranial pressure, capillary leak, and leakage across the blood-brain barrier. One may actually sense the head and neck feeling warm, a generalized pressure within the cranium, and an uncomfortable "brain fog".
4. As an autistic individual one should be seeking out low-glycemic foods, good fats, and lean protein sources...and when that isn't possible, minimize the volume of food. Some may even use fasting and timed-eating strategies to minimize the average blood sugar and insulin throughout the day. The production of ketones within this context, may actually be a desirable strategy...using fats to create gluconeogenesis and ketones. Both processes minimize insulin production, increase insulin sensitivity, and ketones are actually a more efficient intracellular fuel source than glucose.
The issue is not glucose, but rather under what conditions it was produced, how it was produced, in what quantities, and the timing.